Endocrine Abstracts

Rationale: Octreotide is known to shrink acromegalic tumours in vivo. However, the mechanism for this is unclear. To investigate the mechanism of shrinkage we used dynamic contrast enhanced MR imaging (DCE-MRI) to visualise the vascular components within the somatotroph adenomas.Subjects & Methods: Six patients with confirmed acromegaly comprising 4 microadenomas (all male) and 2 macroadenomas (1 male, 1 female) were recruited. All patients we...